The Stanford Cardinal will head to Durham Saturday evening, hoping for a major upset victory over No. 3 Duke Blue Devils. The Cardinal have had a solid debut season in the ACC, finding themselves two games above .500 in conference play with three weeks left in the regular season.
Can they find a way to push Duke to the brink, making it a competitive game in the final minutes, or will the Blue Devils’ defensive efforts suffocate Stanford’s mediocre offensive attack?
Find out below as we make a prediction for the game and break down the spread, total and money line bets.
Stanford vs. Duke Betting Preview
All Stanford vs. Duke odds are from FanDuel Sportsbook and are correct as of Saturday, Feb. 15, 2025.
- Spread
Duke -18.5 - Moneyline
Duke -6000, Stanford +1800 - Over/Under
140.5 points - Game Time
Saturday, Feb. 15, 4 p.m. ET - Location
Cameron Indoor Stadium | Durham, NC - How To Watch
ABC
Stanford enters this contest with a 16-9 overall and 8-6 conference record, good for sixth in the ACC. They’re 12-13 ATS on the season, including just 6-8 in conference play. They’ve been even worse on the road, covering just three of eight road matchups. As of late, the Cardinal have been particularly bad ATS; they haven’t covered in five games.
Not a potent offensive team, only 12 of 25 games on the season have gone over the listed point total. However, eight of 14 conference matchups have reached the over, as well as four of seven outings as the road underdog. The Cardinal are coming off an uninspiring 52-60 loss to the Georgia Tech Yellow Jackets, in which their offense could not find any sort of rhythm.
The Blue Devils, ranked No. 3 in the country, head into this game with a 13-1 ACC record and a 21-3 overall record. Despite a loss last Saturday to the Clemson Tigers, Duke remains in first place in the conference standings.
Having had a number of large spreads this season, the Blue Devils have done well with a 14-10 record ATS. Their 8-6 record ATS in conference and as a home favorite represents a favorable bet.
Duke is a terrific defensive team, and its over/under history reflects that. Only 10 of their 24 games have reached the over—but a middling 50% have gone over in ACC play and at home this season.
Stanford vs. Duke CSN Power Rankings Line
Our power rankings have the Blue Devils slotted at No. 1 due to a combination of excellent defense and explosive offense. The Cardinal are much farther down, occupying the 119th spot.
Vegas has the line set at -18.5, but our power rankings may suggest that line should be higher, especially considering it’s in the comforts of Cameron Indoor Stadium.
Prediction for Stanford vs. Duke
After a loss last Saturday against the Clemson Tigers— their first in over two months— the Blue Devils responded with a 78-57 drubbing of the California Golden Bears at home. They’ll try to do the same against the Cardinal, who have taken three losses in their last four games.
Their loss against the Yellow Jackets was especially disappointing. Georgia Tech is below .500 on the season, yet held Stanford to 30.3% shooting from the field, scoring only 52 points in the road loss. It’ll be hard to shoot the ball much worse against Duke.
Stanford holds the top scorer in the conference in 7-foot-1 center Maxime Raynaud, who’s leading Duke’s Cooper Flagg by just a hair at 19.9 ppg. Raynaud is a terrific finisher around the rim, presenting problems for many teams with his height and length in the paint. He also leads the ACC in rebounds with 11.5 rpg.
Two guards hold it down in the backcourt for the Cardinal. Junior Oziyah Sellers adds 14.0 ppg on solid three-point efficiency, while senior Jaylen Blakes is the second-leading scorer on the team with 14.5 ppg and contributes to a team-leading 5.0 assists per game.
Blakes’ story is of particular interest in this matchup, as he was a member of the Blue Devils for his first three seasons at the college level before joining the Cardinal for his senior season. He averaged only 1.8 ppg last season but has blossomed as a key player for Stanford. It’ll be intriguing to see how his return to Durham plays out.
Duke certainly has the defenders in place to stop Stanford’s attack.
Although only a freshman, 7’2″ center Khaman Maluach is an excellent defender and will try to put a handle on Raynaud. All-world freshman Cooper Flagg, who’s on the short list of Naismith Player of the Year candidates, makes this team go.
Flagg leads the Blue Devils in every major stat category, highlighted by his scoring prowess (19.8 ppg), excellent vision (4.0 apg), and splash-defensive play ability (combined 2.8 steals and blocks per game).
Duke presents intimidating size at all positions, with both starting guards standing at 6-foot-6 and sharp-shooting forward Kon Knueppel at 6-foot-7, alongside the 6-foot-9 Flagg and 7-foot-2 Maluach.
Despite that, I expect the over of 140.5 to be a solid play in this game. The expected final score, according to FanDuel, is 79-61, but Duke has had two lackluster, based on their standards, scoring games of 77 and 78 points in their last two outings.
Similarly, Stanford has not been its best offensively as of late. I’m banking on both teams improving upon their struggles in recent games. I expect Duke to cross the 80-point mark with ease and the Cardinal to compete.
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Building off that, Stanford +18.5 is a solid bet here. They present a versatile offensive attack that Duke hasn’t seen before. The Cardinal may not win the game, but expect them to make it interesting, potentially until the very end.
Picks: Over 140.5, Stanford +18.5
Prediction: Duke 84, Stanford 75
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