The wait is over for Duke fans. Freshman phenom Cooper Flagg will take the court in his first NCAA Tournament game after missing time with a left ankle injury. The Blue Devils (31-3) enter the tournament as a No. 1 seed, riding an 11-game winning streak and looking to make a deep run.
Their first challenge comes against No. 16 seed Mount St. Mary’s (22-12), which secured its tournament spot with a play-in victory.
Duke vs. Mount St. Mary’s Betting Preview
Flagg leads Duke in nearly every statistical category, and his return could be the difference in how far this Blue Devils squad goes.
Meanwhile, the Mountaineers are coming off a five-game win streak and have the momentum of a tournament victory under their belt. Will Duke’s dominance continue, or can Mount St. Mary’s shock the world?
All Duke vs. Mount St. Mary’s odds are from DraftKings Sportsbook and are correct as of Thursday, March 20, 2025.
- Spread: Duke -32.5 (-105) | Mount St. Mary’s +32.5 (-115)
- Moneyline: Duke N/A | Mount St. Mary’s N/A
- Over/Under: 140.5 points (Over -115, Under -105)
- Game Time: Friday, March 21, 2025, 2:50 PM EST
- Location: Lenovo Center | Raleigh, NC
- How to Watch: CBS
Duke has been dominant all season, both straight-up and against the spread (21-10 ATS). They have also hit the over in seven of their last 11 games. Mount St. Mary’s, on the other hand, has won six of its last seven on the moneyline and will try to stay competitive in what oddsmakers expect to be a lopsided affair.
Duke vs. Mount St. Mary’s CSN Winning Probability
- CSN Probability: Duke 98.7% | Mount St. Mary’s 1.3%
This winning probability aligns with Duke’s massive spread and No. 1 seed status. While anything can happen in March Madness, a 16-seed upset is incredibly rare. Vegas and the analytics both indicate a comfortable win for the Blue Devils.
Prediction for Duke vs. Mount St. Mary’s
With Cooper Flagg back in the lineup, Duke should have no problem advancing to the second round. The Blue Devils’ size, talent, and experience vastly outmatch Mount St. Mary’s, which will need a near-perfect game to stay competitive.
Look for Flagg to dominate in his NCAA Tournament debut, while Duke’s defense pressures the Mountaineers into tough shots and turnovers.
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The key for Duke will be maintaining focus and not looking ahead to the next round. If they come out sharp, this game could be over by halftime. Mount St. Mary’s will fight hard, but it’s unlikely to be enough against a powerhouse like Duke.
Prediction: Duke 90, Mount St. Mary’s 59
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