The 2025 NCAA Division I women’s basketball tournament bracket is officially out, and with it comes the need to make as many brackets as possible.
Every region has many talented teams, but which is the strongest? Keep reading for our breakdown of each quadrant of the women’s bracket.

Which Side of the Women’s 2025 NCAA Tournament Bracket Is the Strongest?
1. Regional 4 – Spokane
There are levels to this bracket game, which is clearly above the rest. With two of the best players in the country — USC’s JuJu Watkins and UConn’s Paige Bueckers — set to battle it out in the Elite Eight if all goes to plan, this is clearly the bracket to keep your eye on.
Both teams have been hot lately, but with the Huskies going 21-1 down the stretch and a healthy core, it will be hard to bet against them in this region.
Kansas State ranks No. 9 in the country in NET and feels severely underrated as a No. 5 seed. Iowa, at the No. 6 seed, has a Final Four pedigree and faces a tough matchup with the Missouri Valley Conference champion, No. 11 Murray State.
The No. 3 Oklahoma Sooners have a solid core, led by 6’4” junior center Raegan Beers, and have kept it close with everyone not named South Carolina this year.
2. Regional 3 – Birmingham
On the power of the two Texas-based teams alone (No. 1 Texas and No. 2 TCU), this region looks to be a tough one already. Throw in No. 3 Notre Dame, No. 4 Ohio State, and No. 5 Tennessee into the fray, and you have yourself five top-12 contenders ready to throw down.
While the Longhorns may be the weakest No. 1 seed, this region is stacked — especially in the top five. But the teams at the bottom can also make a run.
No. 14 Stephen F. Austin hasn’t lost since Jan. 18, and No. 12 USF booked themselves a tough slate of non-conference games to prepare for this moment, looking competitive against No. 7 Louisville and South Carolina.
3. Regional 1 – Spokane
Despite the best team in the country — No. 1 UCLA — taking the lead, the depth in the first regional simply doesn’t stack up to that of Regionals 2 and 3. While No. 2 NC State and No. 3 LSU are formidable opponents, they simply don’t stack up to the heat in other regions.
No. 7 Michigan State could be prone to a Cinderella run, but a tough matchup against a No. 10 Harvard team that won the Ivy League’s regular season and tournament titles could spell an end to their hopes early. No. 11 George Mason is also on upset watch. With a 21st in the country rating at the three-ball, they can get hot and dangerous.
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4. Regional 2 – Birmingham
The defending champion No. 1 South Carolina Gamecocks will have the easiest road to the Final Four. No. 2 Duke is considered by many to be the weakest two-seed in the tournament, No. 3 North Carolina has lost three of five and No. 4 Maryland is buried at 28th in the NET rankings.
No. 12 Green Bay could pose a threat to No. 5 Alabama with a 22-game win streak and a solid defense to boot. The Gamecocks would face either No. 8 Utah or No. 9 Indiana in the second round, both of whom have lost three of their last five.
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