The Women’s March Madness Round of 64 features an intriguing matchup between No. 11 Murray State and No. 6 Iowa. The Racers enter the tournament riding a 10-game winning streak and boast one of the country’s most efficient three-point shooting offenses. Meanwhile, despite no longer having Caitlin Clark, Iowa remains a formidable contender with a strong tournament pedigree.
The Hawkeyes have won five straight opening-round games and are 16-5 in the NCAA Tournament since 2019. With Murray State looking to make history and Iowa aiming to continue its dominance, this game has the potential to be one of the most exciting first-round battles. Can the Racers’ sharpshooting propel them to an upset, or will the Hawkeyes’ experience be too much to handle?
Murray State vs. Iowa Betting Preview
All Murray State vs. Iowa odds are from DraftKings Sportsbook and are correct as of Friday, March 21, 2025.
- Spread: Iowa -9.5 (-108) | Murray State +9.5 (-112)
- Moneyline: Iowa -472 | Murray State +355
- Over/Under: 165.5 (-110)
- Game Time: Saturday, March 22, Noon ET
- Location: Lloyd Noble Center | Norman, Okla.
- How To Watch: ESPN
Iowa enters this matchup as a 9.5-point favorite, which reflects their status as a more battle-tested program with tournament experience. However, the Racers are riding high, having won 10 straight games and setting a program record with 25 wins this season.
The Hawkeyes’ ability to score efficiently, averaging 74.3 points per game, gives them an edge, but Murray State’s three-point shooting prowess—ranking 31st nationally in percentage—could keep this one closer than expected.
Murray State vs. Iowa CSN Winning Probability
- CSN Winning Probability: Iowa 76%, Murray State 24%
According to CSN’s probability model, Iowa is a strong favorite, with a 76% chance of advancing to the second round. This aligns with Vegas’ -472 moneyline odds in favor of the Hawkeyes. However, Murray State’s outside shooting gives them a puncher’s chance, particularly if they can capitalize on a hot start.
Prediction for Murray State vs. Iowa
This game will likely come down to whether Murray State can dictate the pace and capitalize on their three-point shooting. If the Racers get hot from deep, they can keep it competitive and potentially cover the spread.
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However, Iowa’s depth and overall scoring ability give them the upper hand in a game where experience matters. Look for the Hawkeyes to control the boards and get enough defensive stops to secure a victory.
Prediction: Iowa 82, Murray State 71
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