LSU vs. Ole Miss is one of the most highly anticipated matchups of Week 5 of the college football season. The No. 4-ranked Tigers will travel to take on the No. 13-ranked Rebels in a battle between two teams at the top of the SEC. Here is everything you need to know about the upcoming matchup.
LSU vs. Ole Miss Odds
The game is viewed as nearly dead even, with Ole Miss as a -114 favorite, according to FanDuel. However, LSU still gets minus odds at -105.
LSU vs. Ole Miss Best Bets
With the teams so even, it is hard to find good bets in this matchup. You need to get creative, which is why we like Garret Nussmeier, 3+ passing touchdowns (+182).
Garrett Nussmeier isn’t the QB1 America wants. But he’s the QB1 America is getting.
No one commands an offense like this kid.
🎦 Draft profile below pic.twitter.com/asSFMojcPe
— ctc1_scouting (@_cutcall) September 23, 2025
LSU vs. Ole Miss Projected Starting Lineup For Week 5
LSU Tigers Starting Lineup
| WR-X | Zavion Thomas |
| WR-Z | Aaron Anderson |
| WR-W | Chris Hilton Jr. |
| LT | Tyree Adams |
| LG | Paul Mubenga |
| C | Braelin Moore |
| RG | Josh Thompson |
| RT | Weston Davis |
| TE | Bauer Sharp |
| QB | Garrett Nussmeier |
| RB | Caden Durham |
| LDE | Jack Pyburn |
| LDT | Dominick McKinley |
| RDT | Bernard Gooden |
| RDE | Patrick Payton |
| WLB | Whit Weeks |
| MLB | West Weeks |
| STAR | Harold Perkins Jr. |
| LCB | Mansoor Delane |
| SS | A.J. Haulcy |
| FS | Tamarcus Cooley |
| RCB | PJ Woodland |
| P | Grant Chadwick |
| K | Damian Ramos |
Ole Miss Rebels Starting Lineup
| WR-X | Harrison Wallace III |
| WR-Z | De’Zhaun Stribling |
| WR-Y | Cayden Lee |
| LT | Diego Pounds |
| LG | Delano Townsend |
| C | Brycen Sanders |
| RG | Patrick Kutas |
| RT | Jayden Williams |
| TE | Dae’Quan Wright |
| QB | Austin Simmons |
| RB | Kewan Lacy |
| DE | Kam Franklin |
| NT | Will Echoles |
| DT | Zxavian Harris |
| BUCK | Suntarine Perkins |
| WLB | Jaden Yates |
| MLB | TJ Dottery |
| LCB | Antonio Kite |
| SS | Nick Cull |
| FS | Sage Ryan |
| RCB | Chris Graves Jr. |
| NB | Kapena Gushiken |
| P | Oscar Bird |
| K | Lucas Carneiro |
LSU vs. Ole Miss Depth Chart For Week 5
LSU Tigers Depth Chart
| WR-X | Nic Anderson | Destyn Hill | — |
| WR-Z | Kyle Parker | — | — |
| WR-W | Barion Brown | Kylan Billiot | TaRon Francis |
| LT | Carius Curne | — | — |
| LG | Coen Echols | — | — |
| C | DJ Chester | — | — |
| RG | — | — | — |
| RT | Ory Williams | — | — |
| TE | Trey’Dez Green | Donovan Green | — |
| QB | Michael Van Buren Jr. | Colin Hurley | — |
| RB | Kaleb Jackson | Harlem Berry | Ju’Juan Johnson |
| LDE | Jimari Butler | Kolaj Cobbins | — |
| LDT | Jacobian Guillory II | Shone Washington | — |
| RDT | Ahmad Breaux | Sydir Mitchell | — |
| RDE | Gabriel Reliford | Dylan Carpenter | — |
| WLB | Tylen Singleton | Jaiden Braker | — |
| MLB | Davhon Keys | Zach Weeks | Keylan Moses |
| STAR | Jardin Gilbert | — | — |
| LCB | Ashton Stamps | Ja’Keem Jackson | — |
| SS | Dashawn Spears | — | — |
| FS | Javien Toviano | — | — |
| RCB | DJ Pickett | — | — |
| P | Aeron Burrell | — | — |
| K | Aeron Burrell | — | — |
Ole Miss Rebels Depth Chart
| WR-X | Deuce Alexander | Traylon Ray |
| WR-Z | Izaiah Hartrup | Devin Price |
| WR-Y | Winston Watkins | — |
| LT | Percy Lewis | — |
| LG | PJ Wilkins | Ethan Fields |
| C | John Wayne Oliver | — |
| RG | Terez Davis | Connor Howes |
| RT | Devin Harper | — |
| TE | Trace Bruckler | Caleb Odom |
| QB | Trinidad Chambliss | AJ Maddox |
| RB | Logan Diggs | Damien Taylor |
| DE | Da’Shawn Womack | — |
| NT | Jamarious Brown | — |
| DT | Kamron Beavers | Andrew Maddox |
| BUCK | Princewill Umanmielen | DeeJay Holmes Jr. |
| WLB | Tahj Chambers | — |
| MLB | Tyler Banks | — |
| LCB | Jaylon Braxton | Dante Core |
| SS | TJ Banks | — |
| FS | Anthony Robinson III | — |
| RCB | Ricky Fletcher | Pat Broomfield |
| NB | Wydett Williams Jr. | — |
| P | Mike Baker | — |
| K | Mike Baker | — |
How to Watch LSU vs. Ole Miss
LSU vs. Ole Miss kicks off on Saturday at 3:30 p.m. ET. The game will be broadcast on ABC with a streaming option on Fubo.
Read More:
- Garrett Nussmeier Confesses to Being Scared of Potential ‘Problem’ LSU Might Be Facing in 2025
- Garrett Nussmeier Predicted To Join His Dad in New Orleans in Latest NFL Mock Draft
- Ole Miss HC Lane Kiffin Snags 50-TD QB Trinidad Chambliss, Adds 3-Star CB in Transfer Portal Day 1 Wins
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