The Louisville Cardinals are gearing up for the 2025 season under Jeff Brohm and star quarterback Miller Moss, with a lot of responsibility on his back. Below is the Louisville 2025 Football Schedule based on the latest details.
List 2025 Louisville Cardinals Opponents
Louisville’s 2025 schedule combines home-heavy non-conference games and a demanding ACC lineup. The season starts with three straight home games before a tough road swing, ending in a rivalry clash with Kentucky. Here’s the full schedule:
- August 30 (Sat)
vs. Eastern Kentucky
L&N Federal Credit Union Stadium, Louisville, KY - September 5 (Fri)
vs. James Madison
L&N Federal Credit Union Stadium, Louisville, KY - September 20 (Sat)
vs. Bowling Green
L&N Federal Credit Union Stadium, Louisville, KY - September 27 (Sat)
at Pittsburgh
Pittsburgh, PA
ACC - October 4 (Sat)
vs. Virginia
L&N Federal Credit Union Stadium, Louisville, KY
ACC - October 17 (Fri)
at Miami
Coral Gables, FL
ACC - October 25 (Sat)
vs. Boston College
L&N Federal Credit Union Stadium, Louisville, KY
ACC - November 1 (Sat)
at Virginia Tech
Blacksburg, VA
ACC - November 8 (Sat)
vs. California
L&N Federal Credit Union Stadium, Louisville, KY
ACC - November 14 (Fri)
vs. Clemson
L&N Federal Credit Union Stadium, Louisville, KY
ACC - November 22 (Sat)
at SMU
Dallas, TX
ACC - November 29 (Sat)
vs. Kentucky
L&N Federal Credit Union Stadium, Louisville, KY
Will Miller Moss Be the Answer for Louisville?
Miller Moss, the USC transfer, steps in with 2,555 passing yards and 18 touchdowns from 2024, plus a memorable 6-TD Holiday Bowl outing against Louisville in 2023. His accuracy and fit in Brohm’s system could dominate early games against Eastern Kentucky, James Madison, and Bowling Green.
Yet, the ACC stretch, featuring Miami, Clemson, Virginia Tech, and the Kentucky finale, will test his turnover tendencies (9 INTs in 2024) and pocket-bound style. With a favorable home slate (7 of 12 games at L&N Stadium), Moss has a shot at 9-10 wins.
KEEP READING: T Wisconsin 2025 Football Schedule: Badgers Need a Bounce Back
Find all the latest college football schedules, including week-by-week breakdowns for every 2025 season slate released. As official times are confirmed, our schedules will be updated accordingly.
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