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    College Football Predictions For Every Top 25 Team: Best Bets, Props, and Picks For Week 2

    With the Week 2 AP Poll out, the opening weekend delivered anticipated changes following a chaotic Week 1. Ohio State vaulted to No. 1, Texas tumbled to No. 7, and newcomers like Florida State, Utah, and Illinois crashed the rankings. As we head into week two, here are the best bets for every top-25 team playing this weekend.

    #1 Ohio State vs. Grambling State

    Grambling State allowed 38 points in Week 1, and OSU is a heavy favorite. Expect fireworks from the Buckeyes, who were pretty limited in production last week against Texas.

    Bet: Over 55.5 Total Points

    2. #2 Penn State vs. FIU

    Penn State rolled 46–11 in their opener. FIU’s defense struggled last season, making this a safe blowout chalk.

    Bet: PSU -41.5

    3. #3 LSU vs. Louisiana Tech

    After upsetting Clemson, LSU hosts a much weaker Louisiana Tech; this should easily go the Tigers’ way.

    Bet: LSU -36.5

    #5 Miami vs. Bethune-Cookman

    Miami should carry its momentum in an easy win against an FCS opponent.

    Bet: Miami -28

    6. #6 Oregon vs. Oklahoma State

    A few years ago, this could have been a brutal home opener for the Ducks. Now there is a fair amount of uncertainty in Stillwater, which gives the nod to the Ducks.

    Bet: Oregon -28.5

    #7 Texas vs. San Jose State

    36.5 is way too many points against a Texas team that is still finding its footing. The offense should bounce back, but San Jose State should cover here.

    Bet: San Jose State +36.5

    #8 Clemson vs. Troy

    Clemson is in a bounce-back spot after LSU held them to nothing in the second half.
    Bet: Clemson -32.5

    #10 South Carolina vs. SC State

    The Gamecocks are coming off an impressive win against Virginia Tech and should have the advantage in this lopsided rivalry.

    Bet: South Carolina -30

    #11 Illinois at Duke

    This is expected to be a tight game, but if Illinois wants to fight for a CFP spot, this win will be needed. Luke Altmyer gives them the advantage on the road.

    Bet: Illinois ML -155

    #12 Arizona State at Mississippi State

    Sam Leavitt threw for 257 yards last week, and the Bulldogs’ secondary struggled against Southern Mississippi.

    Best bet: Sam Leavitt Over 231.5 Passing Yards

    #13 Florida vs. South Florida

    USF was thoroughly impressive in their win vs Boise State. Their defense could pose problems for DJ Lagway early in this one.

    Bet: USF +17.5

    #15 Michigan at #18 Oklahoma

    John Mateer threw for 392 yards in Oklahoma’s opening victory. The Sooners seem to have a capable offense against a freshman quarterback in Bryce Underwood on the other side.

    Bet: Oklahoma -5.5

    #16 Iowa State vs. Iowa

    This game tends to be low scoring, but Iowa has been trending offensively.

    Bet: Over 41.5 total points

    #17 SMU vs Baylor

    SMU dominated their opening weekend, and Baylor got trashed by Auburn in week 1. The Bears seem to have no answer to mobile quarterbacks, and Kevin Jennings is on the other side.

    Bet: SMU -2.5

    #19 Texas A&M vs Utah State

    Aggies struggled to run the ball vs UTSA, and Utah State held UTEP to 103 rushing yards. The battle of the Aggies could be closer than many anticipate.

    Bet: Utah State +31.5

    #20 Ole Miss at Kentucky

    Austin Simmons looked impressive, throwing for 341 yards in his debut start for the Rebels. This should be an easy first SEC test for him.

    Bet: Ole Miss -10

    #21 Alabama vs Louisiana-Monroe Warhawks

    Kalen DeBoer should come into this game with a lot of fire following Alabama’s shocking loss to Florida State.

    Bet: Alabama -37.5

    #23 Indiana vs Kennesaw State

    After early struggles last week, Indiana should come out red hot against Kennesaw State.

    Bet: Indiana -35.5

    #24 Texas Tech vs Kent State

    Behnren Morton seems to be questionable for Saturday’s game after an injury in the first game. 48.5 is too many points if you’re potentially missing your starting quarterback.

    Bet: Kent State +48.5

    Bottom Line

    Week 2 brings some intriguing matchups and light rivalries for an entertaining weekend ahead. With an action-packed weekend, Week 2 should continue to reveal contenders and pretenders.

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