Duke pulled off the largest comeback in Final Four history during its 2001 semifinal matchup with Maryland. Down 39–17 late in the first half, the Blue Devils surged back behind the leadership of Shane Battier and Jay Williams.
In the 1989 semifinals, Seton Hall erased an 18-point deficit against Duke. The Pirates used a relentless full-court press and a balanced offensive attack, including 26 points from John Morton, to dominate the remainder of the game.
Kansas trailed 40–25 late in the first half of the 2022 title game and faced a 15-point halftime deficit. Then the Jayhawks came alive defensively, holding UNC to just 29 second-half points.
Loyola Chicago’s 1963 title came after a rally from 15 points down in the second half against Cincinnati. Jerry Harkness led the comeback, forcing overtime with a clutch basket.
San Diego State trailed 56–42 with 13:53 left in its 2023 semifinal against Florida Atlantic. The Aztecs surged with a 30–15 closing run, capped by Lamont Butler’s game-winning buzzer-beater.
A new entry on the list. Down 14 points with 8:17 to play, Houston stunned Duke 70–67 behind a relentless defensive stand—allowing just one field goal in the final 10 minutes. LJ Cryer poured in 26 points, and J’Wan Roberts hit two go-ahead free throws with 19.6 seconds remaining.