A full slate of midweek MACtion mayhem. Two SEC titans slugging it out with College Football Playoff implications. A top-tier ACC matchup. Everywhere you look in college football Week 12 there’s an engaging storyline that could dictate the postseason outlook, and we’ve predicted the scoreline of every single one of the matchups set to dominate headlines this week.
We compiled our college football predictions for Week 12 using the College Football Network Playoff Predictor, and you can too! Predict a conference, predict every game, or simulate the entire season to discover which 12 teams will make the 2024-2025 College Football Playoff. Get started right now!
East Carolina vs. Tulsa Prediction
- Prediction: East Carolina 33, Tulsa 23
- Betting Lines: East Carolina -14
- TV Channel: ESPN
Full betting preview: East Carolina vs. Tulsa Prediction: Katin Houser and His Dynamic WR Duo Go Hurricane Hunting on Thursday Night
Wyoming vs. Colorado State Prediction
- Prediction: Wyoming 16, Colorado State 35
- Betting Lines: Colorado State -10
- TV Channel: CBS Sports Network
Full betting preview: Wyoming vs. Colorado State Prediction: Avery Morrow Leads the Rams Charge in the Border War
North Texas vs. UTSA Prediction
- Prediction: North Texas 33, UTSA 17
- Betting Lines: North Texas -1.5
- TV Channel: ESPN2
Full betting preview: North Texas vs. UTSA Prediction: Who Wins in a Potential Shootout?
UCLA vs. Washington Prediction
- Prediction: UCLA 10, Washington 27
- Betting Lines: Washington -3.5
- TV Channel: Fox
Full betting preview: UCLA vs. Washington: Former Pac-12 Foes Clash in First Big Ten Battle
Houston vs. Arizona Prediction
- Prediction: Houston 33, Arizona 30
- Betting Lines: Arizona -1.5
- TV Channel: FS1
Full betting preview: Houston vs. Arizona Prediction: Bowl Aspirations on the Line in Big 12 Battle
Ohio State vs. Northwestern Prediction
- Prediction: Ohio State 33, Northwestern 15
- Betting Lines: Ohio State -30.5
- TV Channel: Big Ten Network
Texas vs. Arkansas Prediction
- Prediction: Texas 39, Arkansas 21
- Betting Lines: Texas -16.5
- TV Channel: ABC
Clemson vs. Pittsburgh Prediction
- Prediction: Clemson 13, Pittsburgh 27
- Betting Lines: Clemson -10
- TV Channel: ESPN
Utah vs. Colorado Prediction
- Prediction: Utah 24, Colorado 34
- Betting Lines: Colorado -10
- TV Channel: Fox
Liberty vs. UMass Prediction
- Prediction: Liberty 31, UMass 14
- Betting Lines: Liberty -14
- TV Channel: ESPN+
Louisiana Tech vs. Western Kentucky Prediction
- Prediction: Louisiana Tech 15, Western Kentucky 31
- Betting Lines: Western Kentucky -13
- TV Channel: CBS Sports Network
Tulane vs. Navy Prediction
- Prediction: Tulane 13, Navy 21
- Betting Lines: Tulane -6.5
- TV Channel: ESPN2
Louisiana-Monroe vs. Auburn Prediction
- Prediction: Louisiana-Monroe 27, Auburn 40
- Betting Lines: Auburn -24
- TV Channel: SEC Network
Coastal Carolina vs. Marshall Prediction
- Prediction: Coastal Carolina 21, Marshall 39
- Betting Lines: Marshall -9
- TV Channel: ESPN+
Murray State vs. Kentucky Prediction
- Prediction: Murray State 21, Kentucky 33
- Betting Lines: No line available
- TV Channel: ESPN+
Mercer vs. Alabama Prediction
- Prediction: Mercer 17, Alabama 35
- Betting Lines: No line available
- TV Channel: ESPN+
FIU vs. Jacksonville State Prediction
- Prediction: FIU 20, Jacksonville State 40
- Betting Lines: Jacksonville State -14
- TV Channel: ESPN+
Florida Atlantic vs. Temple Prediction
- Prediction: Florida Atlantic 29, Temple 13
- Betting Lines: Temple -1.5
- TV Channel: ESPN+
Michigan State vs. Illinois Prediction
- Prediction: Michigan State 19, Illinois 39
- Betting Lines: Illinois -3
- TV Channel: FS1
Syracuse vs. California Prediction
- Prediction: Syracuse 21, California 37
- Betting Lines: California -7.5
- TV Channel: The CW Network
Sam Houston vs. Kennesaw State Prediction
- Prediction: Sam Houston 23, Kennesaw State 10
- Betting Lines: Sam Houston -13
- TV Channel: ESPN+
Hawaii vs. Utah State Prediction
- Prediction: Hawaii 33, Utah State 31
- Betting Lines: Hawaii -2.5
- TV Channel: Spectrum Sports
Penn State vs. Purdue Prediction
- Prediction: Penn State 40, Purdue 21
- Betting Lines: Penn State -28
- TV Channel: CBS
Virginia vs. Notre Dame Prediction
- Prediction: Virginia 21, Notre Dame 34
- Betting Lines: Notre Dame -23.5
- TV Channel: NBC
Boston College vs. SMU Prediction
- Prediction: Boston College 20, SMU 39
- Betting Lines: SMU -16.5
- TV Channel: ESPN
LSU vs. Florida Prediction
- Prediction: LSU 31, Florida 15
- Betting Lines: LSU -4.5
- TV Channel: ABC
Louisville vs. Stanford Prediction
- Prediction: Louisville 40, Stanford 30
- Betting Lines: Louisville -20.5
- TV Channel: ACC Network
Oregon State vs. Air Force Prediction
- Prediction: Oregon State 39, Air Force 24
- Betting Lines: Oregon State -4.5
- TV Channel: CBS Sports Network
South Florida vs. Charlotte Prediction
- Prediction: USF 30, Charlotte 14
- Betting Lines: South Florida -3
- TV Channel: ESPN+
Nebraska vs. USC Prediction
- Prediction: Nebraska 20, USC 35
- Betting Lines: USC -9.5
- TV Channel: Fox
Baylor vs. West Virginia Prediction
- Prediction: Baylor 24, West Virginia 35
- Betting Lines: Baylor -1.5
- TV Channel: ESPN2
Troy vs. Georgia Southern Prediction
- Prediction: Troy 20, Georgia Southern 35
- Betting Lines: Georgia Southern -8
- TV Channel: ESPN+
James Madison vs. Old Dominion Prediction
- Prediction: James Madison 39, Old Dominion 29
- Betting Lines: James Madison -3.5
- TV Channel: ESPNU
Missouri vs. South Carolina Prediction
- Prediction: Missouri 13, South Carolina 24
- Betting Lines: South Carolina -13.5
- TV Channel: SEC Network
Arkansas State vs. Georgia State Prediction
- Prediction: Arkansas State 28, Georgia State 18
- Betting Lines: Georgia State -1.5
- TV Channel: ESPN+
Rutgers vs. Maryland Prediction
- Prediction: Rutgers 31, Maryland 16
- Betting Lines: Maryland -3.5
- TV Channel: FS1
Boise State vs. San Jose State Prediction
- Prediction: Boise State 38, San Jose State 26
- Betting Lines: Boise State -13.5
- TV Channel: CBS Sports Network
Arizona State vs. Kansas State Prediction
- Prediction: Arizona State 40, Kansas State 27
- Betting Lines: Kansas State -8
- TV Channel: ESPN
South Alabama vs. Louisiana Prediction
- Prediction: South Alabama 10, Louisiana 24
- Betting Lines: Louisiana -9
- TV Channel: ESPN+
Southern Miss vs. Texas State Prediction
- Prediction: Texas State 37, Southern Miss 18
- Betting Lines: Texas State -27
- TV Channel: ESPN+
Oregon vs. Wisconsin Prediction
- Prediction: Oregon 28, Wisconsin 17
- Betting Lines: Oregon -14.5
- TV Channel: NBC
Tennessee vs. Georgia Prediction
- Prediction: Tennessee 39, Georgia 27
- Betting Lines: Georgia -9
- TV Channel: ABC
New Mexico State vs. Texas A&M Prediction
- Prediction: New Mexico State 23, Texas A&M 38
- Betting Lines: Texas A&M -40.5
- TV Channel: SEC Network
Cincinnati vs. Iowa State Prediction
- Prediction: Cincinnati 14, Iowa State 27
- Betting Lines: Iowa State -9
- TV Channel: Fox
Wake Forest vs. North Carolina Prediction
- Prediction: Wake Forest 17, North Carolina 27
- Betting Lines: North Carolina -11.5
- TV Channel: ACC Network
UAB vs. Memphis Prediction
- Prediction: UAB 21, Memphis 35
- Betting Lines: Memphis -15
- TV Channel: ESPN2
Washington State vs. New Mexico Prediction
- Prediction: Washington State 34, New Mexico 14
- Betting Lines: Washington State -13.5
- TV Channel: FS1
Kansas vs. BYU Prediction
- Prediction: Kansas 10, BYU 27
- Betting Lines: BYU -3
- TV Channel: ESPN
San Diego State vs. UNLV Prediction
- Prediction: San Diego State 17, UNLV 37
- Betting Lines: UNLV -20.5
- TV Channel: CBS Sports Network
Ball State vs. Buffalo Prediction
- Result: Ball State 48, Buffalo 51 (OT)
- Prediction: Ball State 35, Buffalo 33
Western Michigan vs. Bowling Green Prediction
- Result: Western Michigan 13, Bowling Green 31
- Prediction: Western Michigan 22, Bowling Green 37
Central Michigan vs. Toledo Prediction
- Result: Central Michigan 10, Toledo 37
- Prediction: Central Michigan 10, Toledo 25
Kent State vs. Miami (OH) Prediction
- Result: Kent State 7, Miami (OH) 34
- Prediction: Kent State 19, Miami (OH) 33
Akron vs. Northern Illinois Prediction
- Result: Akron 16, Northern Illinois 29
- Prediction: Akron 21, Northern Illinois 33
Eastern Michigan vs. Ohio Prediction
- Result: Eastern Michigan 10, Ohio 35
- Prediction: Eastern Michigan 19, Ohio 27
College Football Network has you covered with the latest from the ACC, Big Ten, Big 12, SEC, and every Group of Five conference and FBS Independent program.