The last time the Houston Cougars and Oklahoma Sooners dueled, we were treated to a 49-31 shootout. However, that may not be the case in Week 2.
Here are the latest college football betting odds and final prediction for Houston vs. Oklahoma ahead of the Saturday night clash.
Houston vs. Oklahoma Betting Preview
All Houston vs. Oklahoma odds are from DraftKings Sportsbook and are correct as of Saturday, Sept. 7.
- Spread
Oklahoma -27.5 - Moneyline
Oklahoma -4000, Houston +1600 - Over/Under
49.5 points - Game time
7:45 p.m. ET - Location
Memorial Stadium, Norman, Oklahoma - Predicted Weather at Kick
79 degrees, 11 mph winds, sunny - How To Watch
SEC Network
Houston and Oklahoma will face off for the first time since 2019 and just the third time in the last two decades. The Sooners own a 3-1 all-time advantage, and given that they’re nearly 30-point favorites in Norman, they’ll likely make it 4-1.
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Oklahoma has covered the spread in seven of its last eight games at home, while Houston has failed to cover in six of its last eight games against AP-ranked opponents.
The total opened at 55.5 but has quickly fallen to under 50, and the spread grew three points from 26 to 29 in favor of the Sooners, likely due to the Cougars’ performance in a Week 1 loss to UNLV.
Prediction for Houston vs. Oklahoma
Oklahoma cruised to a dominant 51-3 victory over Temple in Week 1, but the win wasn’t without concerns. The Sooners struggled on third down, converting just 1 of 12 attempts, and redshirt freshman quarterback Jackson Arnold managed only 5.6 yards per pass attempt.
While the scoreline was impressive, these issues could pose problems against tougher competition.
Houston is expected to provide more resistance, especially on the ground. Oklahoma’s rushing attack, led by Gavin Sawchuk and others, averaged an impressive 6.1 yards per carry against Temple.
If the Cougars manage to slow the ground game, the pressure will be on Arnold to step up through the air. In that case, wide receivers Deion Burks and Nic Anderson—who missed Week 1 due to an undisclosed injury—along with tight end Bauer Sharp, will become key players for Oklahoma’s passing offense.
On the other side, Houston’s offense was lackluster in their 7-point showing against UNLV.
Quarterback Donovan Smith, regarded by some as a potential sleeper in the NFL Draft, struggled mightily, completing just 50% of his passes for 135 yards with no touchdowns and two interceptions. To make matters worse, the offensive line allowed six sacks and failed to create any running lanes, resulting in a dismal 1.5 yards per rush.
Houston isn’t upsetting Oklahoma in this one.
While the Sooners have some issues to iron out, Brent Venables has his squad rolling early in the season. The -29 spread may seem steep, but given Houston’s offensive struggles in Week 1, Oklahoma has the edge in all facets of the game.
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Expect the Sooners to cover and potentially hit the over on their own. The Cougars might add a late score or two, making the over even more appealing.
Prediction: Oklahoma 45, Houston 13
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