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    College Football Predictions Week 10: Projecting Every Single Game Including Ohio State vs. Penn State, Louisville vs. Clemson

    Our college football predictions for Week 10 break down the score projections for every single game of an exciting week of action.

    College football Week 10 is upon us, and by this time of year, we normally have a solid idea of who’s good, bad, and downright ugly. However, in this wildest of seasons, predicting who will win each week isn’t the easiest of tasks. Nonetheless, we’ve predicted the winner and scoreline of every Week 10 game.

    We compiled our college football predictions for Week 10 using the College Football Network Playoff Predictor, and you can too! Predict a conference, predict every game, or simulate the entire season to discover which 12 teams will make the 2024-2025 College Football Playoff. Get started right now!

    CFN CFB Playoff Predictor
    College Football Network’s College Football Playoff Predictor is a tool that allows you to play out various weekly scenarios to see how the CFP picture changes with each scenario.

    Ohio State vs. Penn State Prediction

    • Prediction: Ohio State 33, Penn State 23
    • Betting Lines: Ohio State -4
    • TV Channel: Fox

    Duke vs. Miami (FL) Prediction

    • Prediction: Duke 15, Miami (FL) 30
    • Betting Lines: Miami (FL) -20
    • TV Channel: ABC

    Ole Miss vs. Arkansas Prediction

    • Prediction: Ole Miss 33, Arkansas 21
    • Betting Lines: Ole Miss -6.5
    • TV Channel: ESPN

    Air Force vs. Army Prediction

    • Prediction: Air Force 21, Army 35
    • Betting Lines: Army -23.5
    • TV Channel: CBS

    Minnesota vs. Illinois Prediction

    • Prediction: Minnesota 19, Illinois 33
    • Betting Lines: Minnesota -2
    • TV Channel: FS1

    Northwestern vs. Purdue Prediction

    • Prediction: Northwestern 19, Purdue 33
    • Betting Lines: Northwestern -1.5
    • TV Channel: Big Ten Network

    Stanford vs. NC State Prediction

    • Prediction: Stanford 21, NC State 40
    • Betting Lines: NC State -10
    • TV Channel: ACC Network

    Virginia Tech vs. Syracuse Prediction

    • Prediction: Virginia Tech 27, Syracuse 31
    • Betting Lines: Virginia Tech -4
    • TV Channel: The CW Network

    Buffalo vs. Akron Prediction

    • Prediction: Buffalo 40, Akron 20
    • Betting Lines: Buffalo -1
    • TV Channel: CBS Sports Network

    Toledo vs. Eastern Michigan Prediction

    • Prediction: Toledo 21, Eastern Michigan 10
    • Betting Lines: Toledo -8
    • TV Channel: ESPNU

    Memphis vs. UTSA Prediction

    • Prediction: Memphis 39, UTSA 20
    • Betting Lines: Memphis -8
    • TV Channel: ESPN2

    Vanderbilt vs. Auburn Prediction

    • Prediction: Vanderbilt 40, Auburn 21
    • Betting Lines: Auburn -6.5
    • TV Channel: SEC Network

    Maine vs. Oklahoma Prediction

    • Prediction: Maine 21, Oklahoma 44
    • Betting Lines: No line available
    • TV Channel: ESPN+

    Old Dominion vs. Appalachian State Prediction

    • Prediction: Old Dominion 30, Appalachian State 13
    • Betting Lines: Old Dominion -2.5
    • TV Channel: ESPN+

    Tulsa vs. UAB Prediction

    • Prediction: Tulsa 38, UAB 19
    • Betting Lines: UAB -3.5
    • TV Channel: ESPN+

    Oregon vs. Michigan Prediction

    • Prediction: Oregon 31, Michigan 17
    • Betting Lines: Oregon -14.5
    • TV Channel: CBS/Paramount+

    Florida vs. Georgia Prediction

    • Prediction: Florida 21, Georgia 31
    • Betting Lines: Georgia -16.5
    • TV Channel: ABC

    Texas Tech vs. Iowa State Prediction

    • Prediction: Texas Tech 24, Iowa State 37
    • Betting Lines: Iowa State -14.5
    • TV Channel: ESPN

    Indiana vs. Michigan State Prediction

    • Prediction: Indiana 28, Michigan State 10
    • Betting Lines: Indiana -7
    • TV Channel: Peacock

    Kansas State vs. Houston Prediction

    • Prediction: Kansas State 39, Houston 24
    • Betting Lines: Kansas State -13
    • TV Channel: Fox

    UCLA vs. Nebraska Prediction

    • Prediction: UCLA 24, Nebraska 38
    • Betting Lines: Nebraska -7.5
    • TV Channel: Big Ten Network

    North Carolina vs. Florida State Prediction

    • Prediction: North Carolina 34, Florida State 17
    • Betting Lines: North Carolina -2
    • TV Channel: ACC Network

    Arizona vs. UCF Prediction

    • Prediction: Arizona 26, UCF 23
    • Betting Lines: UCF -6.5
    • TV Channel: FS1

    Middle Tennessee vs. UTEP Prediction

    • Prediction: Middle Tennessee 30, UTEP 33
    • Betting Lines: UTEP -3
    • TV Channel: CBS Sports Network

    Louisiana-Monroe vs. Marshall Prediction

    • Prediction: Louisiana-Monroe 40, Marshall 27
    • Betting Lines: Marshall -10.5
    • TV Channel: ESPN+

    Wyoming vs. New Mexico Prediction

    • Prediction: Wyoming 34, New Mexico 31
    • Betting Lines: New Mexico -7
    • TV Channel: TruTV/Max

    Coastal Carolina vs. Troy Prediction

    • Prediction: Coastal Carolina 26, Troy 14
    • Betting Lines: Coastal Carolina -4.5
    • TV Channel: ESPN+

    Navy vs. Rice Prediction

    • Prediction: Navy 37, Rice 21
    • Betting Lines: Navy -13
    • TV Channel: ESPN2

    UMass vs. Mississippi State Prediction

    • Prediction: UMass 17, Mississippi State 35
    • Betting Lines: Mississippi State -18
    • TV Channel: SEC Network

    Arizona State vs. Oklahoma State Prediction

    • Prediction: Arizona State 17, Oklahoma State 21
    • Betting Lines: Arizona State -1
    • TV Channel: FS1

    Hawaii vs. Fresno State Prediction

    • Prediction: Hawaii 20, Fresno State 34
    • Betting Lines: Fresno State -13
    • TV Channel: Spectrum Sports

    Texas A&M vs. South Carolina Prediction

    • Prediction: Texas A&M 24, South Carolina 13
    • Betting Lines: Texas A&M -3.5
    • TV Channel: ABC

    Louisville vs. Clemson Prediction

    • Prediction: Louisville 17, Clemson 34
    • Betting Lines: Clemson -11.5
    • TV Channel: ESPN

    Wisconsin vs. Iowa Prediction

    • Prediction: Wisconsin 27, Iowa 31
    • Betting Lines: Iowa -3.5
    • TV Channel: NBC

    USC vs. Washington Prediction

    • Prediction: USC 14, Washington 27
    • Betting Lines: USC -2.5
    • TV Channel: Big Ten Network

    Georgia Southern vs. South Alabama Prediction

    • Prediction: Georgia Southern 23, South Alabama 40
    • Betting Lines: South Alabama -6
    • TV Channel: ESPNU

    Kentucky vs. Tennessee Prediction

    • Prediction: Kentucky 14, Tennessee 27
    • Betting Lines: Tennessee -16
    • TV Channel: SEC Network

    Pittsburgh vs. SMU Prediction

    • Prediction: Pittsburgh 34, SMU 27
    • Betting Lines: SMU -7.5
    • TV Channel: ACC Network

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    TCU vs. Baylor Prediction

    • Prediction: TCU 27, Baylor 14
    • Betting Lines: Baylor -3
    • TV Channel: ESPN2

    Colorado State vs. Nevada Prediction

    • Prediction: Colorado State 37, Nevada 23
    • Betting Lines: Colorado State -1
    • TV Channel: CBS Sports Network

    New Mexico State vs. Florida International Prediction

    • Result: New Mexico State 13, Florida International 34
    • Prediction: New Mexico State 24, Florida International 40

    Louisiana vs. Texas State Prediction

    • Result: Louisiana 23, Texas State 17
    • Prediction: Louisiana 33, Texas State 17

    Louisiana Tech vs. Sam Houston Prediction

    • Result: Louisiana Tech 3, Sam Houston 9
    • Prediction: Louisiana Tech 14, Sam Houston 35

    Jacksonville State vs. Liberty Prediction

    • Result: Jacksonville State 31, Liberty 21
    • Prediction: Jacksonville State 17, Liberty 34

    Kennesaw State vs. Western Kentucky Prediction

    • Result: Kennesaw State 14, Western Kentucky 31
    • Prediction: Kennesaw State 14, Western Kentucky 31

    Tulane vs. Charlotte Prediction

    • Result: Tulane 34, Charlotte 3
    • Prediction: Tulane 37, Charlotte 27

    Georgia State vs. UConn Prediction

    • Result: Georgia State 27, UConn 34
    • Prediction: Georgia State 33, UConn 21

    South Florida vs. Florida Atlantic Prediction

    • Result: South Florida 44, Florida Atlantic 21
    • Prediction: South Florida 27, Florida Atlantic 17

    San Diego State vs. Boise State Prediction

    • Result: San Diego State 24, Boise State 56
    • Prediction: San Diego State 21, Boise State 35

    College Football Network has you covered with the latest from the ACC, Big Ten, Big 12, SEC, and every Group of Five conference and FBS Independent program.

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